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SR-121463A 185913-79-5

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品牌: 医药中间体
cas: 185913-79-5
英文名称: SR-121463A
分子式: SR-121463A
单价: 8600.00元/公斤
起订: 1 公斤
供货总量: 1000 公斤
发货期限: 自买家付款之日起 3 天内发货
所在地: 贵州 黔西南布依族苗族自治州
有效期至: 长期有效
最后更新: 2019-03-28 09:52
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SR-121463A  185913-79-5

价格:8600元/公斤 含量:99% 包装:25公斤
CAS;185913-79-5
分子式:C17H22ClNO3
分子量:323.8228
化学名称 N-tert-Butyl-4-[5'-ethoxy-4-[2-(4-morpholinyl)ethoxy]-2'-oxospiro

[cyclohexane-1,3'-indolin]-1'-ylsulfonyl]-3-methoxybenzamide fumarate
The reduction of diethyl 3-(methoxymethoxy)glutarate (I) with LiAlH4 in THF gives 

3-(methoxymethoxy)pentane-1,5-diol (II), which is treated with Ts-OH and TEA in THF 

to yield the disulfonate (III). The condensation of (III) with 5-ethoxyindolin-2-

one (IV) by means of tBu-OK in THF affords the spiro compound (V), which is 

deprotected with HCl in methanol to afford the spiranic alcohol (VI). The oxidation 

of (VI) with pyridinium chlorochromate (PCC) over Al2O3 provides the spiranic 

cyclohexanone (VII), which is treated with 2-chloroethanol (VIII) and Ms-OH in 

toluene to give the ketal (IX). The reaction of (IX) with zinc borohydride and 

trimethylsilyl chloride in ethyl ether/dichloromethane yields the 2-chloroethoxy 

derivative (X), which is condensed with 4-(N-tert-butylcarbamoyl)-2-

methoxybenzenesulfonyl chloride (XI) by means of tBu-OK in THF to afford the adduct 

(XII). Finally, the target compound is obtained by condensation of (XII) with 

morpholine (XIII) by means of NaI in DMF, followed by treatment with fumaric acid.

Bromophenylethylketone 23022-83-5
Alpha 2114-00-3
UR 1431 Hydrochloride 49656-78-2
3-Chloropropiophenone 936-59-4
propiophenone 93-55-0
Chloroephedrine HCL 110925-64-9
chloroephedrine 27270-80-0
PHENYLPROPANOLAMINE 14838-15-4
甲鞍基笨柄酮 2538-50-3
Topiroxostat 577778-58-6
THC 1972-08-3
MDA 4764-17-4
MDMA 42542-10-9 
GHB 591-81-1
nimetazepam 2011-67-8
desomorphine 427-00-9 
triazolam 28911-01-5
Thionyl chloride 7719-09-7
EPHEDRINE 299-42-3
EINECS 269-531-5
aniracetam 72432-10-1
Chloroephedrine HCL 110925-64-9
hydrochloride 27270-80-0
chloroephedrine 25394-33-6
Loratadine 79794-75-5
Ephedrine hydrochloride 50-98-6
ENDO-NORBORNEO 134-71-4
4-hydroxyephedrine-hydrochloride 7437-54-9
Ephedrol 24221-86-1
Mapenterol hydrochloride 54238-51-6
L-PAC 1798-60-3
UNII-Y24T9BT2Q2 33817-09-3
6-MDMA 138808-79-4
methylamphetamine 64-11-9
methamphetamine-D5 60124-88-1
MDMA hydrochloride salt
Methamphetamine 4846-07-5
desoxyn 51-57-0 
(S)-METHYLENEDIOXYMETHAMPHETAMINE 66142-89-0
4-phenylbutan-2-amine 22374-89-6
3,4-Methylenedioxy Methamphetamine Hydrochloride 64057-70-1
rac Pholedrine 370-14-9 
methamphetamine 537-46-2
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